I. 投稿論文
I.I 原著論文 （*は責任著者を示します）
2021年
Hung Wei Lai, Kiwamu
Takahashi, Motowo Nakajima, Tohru Tanaka, Shun-ichiro Ogura*
Efficiency of
aminolevulinic acid (ALA)-photodynamic therapy based on ALA uptake transporters
in a cell density-dependent malignancy model, Journal of Photochemistry and Photobiology B: Biology, DOI: 10.1016/j.jphotobiol.2021.112191
Taku Nakayama, Tomonori
Sano, Yoshiki Oshimo, Chiaki Kawada, Moe Kasai, Shinkuro Yamamoto, Hideo
Fukuhara, Keiji Inoue, Shun-ichiro Ogura
Enhanced lipid metabolism induces the sensitivity of dormant cancer cells to
5-aminolevulinic acid-based photodynamic therapy, Scientific reports, DOI: 10.1038/s41598-021-86886-9
2020年
Hung Wei Lai, Taku
Nakayama, Shun-ichiro Ogura*
Key transporters leading to specific protoporphyrin IX accumulation in cancer
cell following administration of aminolevulinic acid in photodynamic
therapy/diagnosis, International Journal
of Clinical Oncology, in press DOI: 10.1007/s10147-020-01766-y
Taku Nakayama, Naoko
Nozawa, Chiaki Kawada, Shinkuro Yamamoto, Takuya Ishii, Masahiro Ishizuka,
Tsutomu Namikawa, Shun-ichiro Ogura, Kazuhiro Hanazaki, Keiji Inoue, Takashi
Karashima
Mitomycin C-induced cell cycle arrest enhances 5-aminolevulinic acid-based
photodynamic therapy for bladder cancer, Photodiagnosis
and Photodynamic Therapy, 2020, 31, 101893.DOI: 10.1016/j.pdpdt.2020.101893
2019年
Taku Nakayama, Tatsuya
Kobayashi, Otsuka Shimpei, Hideo Fukuhara, Tsutomu Namikawa, Keiji Inoue,
Kazuhiro Hanazaki, Kiwamu Takahashi, Motowo Nakajima, Tohru Tanaka, Shun-ichiro
Ogura*
Photoirradiation after aminolevulinic acid treatment suppresses cancer cell
proliferation through the HO-1/p21 pathway, Photodiagnosis
and photodynamic therapy, 2019, 28, 10-17.DOI: 10.1016/j.pdpdt.2019.07.021
Hung Wei Lai, Ryuta
Sasaki, Shiro Usuki, Motowo Nakajima, Tohru Tanaka, Shun-ichiro Ogura*
Novel Strategy to Increase Specificity of ALA-Induced PpIX Accumulation through
Inhibition of Transporters Involved in ALA Uptake, Photodiagnosis and photodynamic therapy, 2019,27, 327-335.DOI: 10.1016/j.pdpdt.2019.06.017
Yuki Tsuga, Masataka Katou, Satoshi Kuwabara, Takashi Kanamori, Shun‐ichiro
Ogura, Shigetoshi Okazaki, Hiroyuki Ohtani, Hideya Yuasa
A Twist‐Assisted Biphenyl
Photosensitizer Passable Through Glucose Channel, Chemistry–An Asian Journal, 2019, 14, 2067-2071.DOI: 10.1002/asia.201900378
2018年
Yuta Sugiyama, Yukari Hiraiwa, Yuichiro Hagiya,
Motowo Nakajima, Tohru Tanaka, Shun-ichiro Ogura*
5-Aminolevulinic acid regulates the immune response in LPS-stimulated RAW
264.7 macrophages, BMC immunology, 2018, 19, 41.DOI: 10.1186/s12865-018-0277-5.
Takashi Kanamori, Akira
Matsuyama, Hidenori Naito, Yuki Tsuga, Yoshiki Ozako, Shun-ichiro Ogura,
Shigetoshi Okazaki, Hideya Yuasa
Water-Soluble Glucosyl Pyrene Photosensitizers: An Intramolecularly Synthesized
2-C-Glucoside and an O-Glucoside, Journal of Organic Chemistry, 2018, 83, 13765–13775, DOI: 10.1021/acs.joc.8b02066.
Akihiro Nomoto, Nozomi
Sakamoto, Yuta Sakai, Keisuke Fukumoto, Shun-ichiro Ogura, Katao Shouhei,
Kiyomi Kakiuchi, Jun-ichi Kikuchi, Shigenobu Yano, Akiya Ogawa
Synthesis and crystal structures of phenylalanine ester-introduced
palladium(II) and platinum(II) complexes and their cytotoxicities, Research on Chemical Intermediates,
2018, DOI: 10.1007/s11164-018-3623-6.
2017年
Yusei Shinohara, Yoshio
Endo, Chiaki Abe, Ikkyu Shiba, Masahiro Ishizuka, Tohru Tanaka, Yutaka
Yonemura, Shun-ichiro Ogura, Masahide Tominaga, Hisatsugu Yamada, Yoshihiro Uto
Development of a novel Schiff base derivative for enhancing the anticancer
potential of 5-aminolevulinic acid-based photodynamic therapy, Photodiagnosis and Photodynamic Therapy,
2017, 20, 182-188, DOI: 10.1016/j.pdpdt.2017.10.014.
Wenqian Wang, Kouichi
Tabu, Yuichiro Hagiya, Yuta Sugiyama, Yasuhiro Kokubu, Yoshitaka Murota,
Shun-ichiro Ogura and Tetsuya Taga
Enhancement of 5-aminolevulinic acid-based fluorescence detection of side
population-defined glioma stem cells by iron chelation, Scientific Reports, 2017, 7, 42070, DOI: 10.1038/srep42070.
Takashi Kanamori, Takashi Sawamura, Tatsumi Tanaka, Izumi Sotokawa, Ryota
Mori, Kotaro Inada, Akihiro Ohkubo, Shun-ichiro Ogura, Yasutoshi Murayama,
Eigo Otsuji and Hideya Yuasa
Coating lanthanide nanoparticles with carbohydrate ligands elicits affinity for
HeLa and RAW264.7 cells, enhancing their photodamaging effect, Bioorganic & Medicinal Chemistry,
2017, 25, 743-749, DOI: 10.1016/j.bmc.2016.11.050.
2016年
Taku Nakayama, Shimpei Otsuka, Tatsuya Kobayashi, Hodaka Okajima, Kentaro
Matsumoto, Yuichiro Hagiya, Keiji Inoue, Taro Shuin, Motowo Nakajima, Tohru
Tanaka and Shun-ichiro Ogura*
Dormant cancer cells accumulate high protoporphyrin IX levels and are sensitive
to 5-aminolevulinic acid-based photodynamic therapy, Scientific Reports, 2016, 6, 36478.
Yutaka Yonemura, Emel Canbay,
Haruaki Ishibashi, Eisei Nishino, Yoshio Endo, Shouzou Sako and Shun-ichiro
Ogura
5-aminolevulinic acid fluorescence in detection of peritoneal metastases, Asian Pacific Journal of Cancer Prevention, 2016,
17, 2271-5.
Junkoh Yamamoto, Shingo
Kaneda, Tetsuya Yoneda, Shun-ichiro Ogura, Shohei Shimajiri, Tohru Tanaka,
Yukinori Korogi and Shigeru Nishizawa
Improving contrast enhancement in magnetic resonance imaging using
5-aminolevulinic acid–induced protoporphyrin IX for high-grade gliomas: A prospective
case study and clinical implications, Oncology Letters, 2017, 13, 1269-1275, DOI: 10.3892/ol.2016.5539.
Tomohiro Osaki, Inoru Yokoe,
Shun-ichiro Ogura, Kiwamu Takahashi, Kiyotaka Murakami, Katsushi Inoue, Masahiro
Ishizuka, Tohru Tanaka, Liming Li, Akihiko Sugiyama, Kazuo Azuma, Yusuke Murahata,
Takeshi Tsuka, Norihiko Ito, Tomohiro Imagawa, Yoshiharu Okamoto
Photodynamic detection of canine mammary gland tumours after oral administration
of 5-aminolevulinic acid, Veterinary and
Comparative Oncology, 2016, DOI: 10.1111/vco.12213.
2015年
Shimpei Otsuka, Kentaro
Matsumoto, Motowo Nakajima, Tohru Tanaka and Shun-ichiro Ogura*
Oxygen availability for porphyrin biosynthesis enzymes determines the
production of protoporphyrin IX (PpIX) during hypoxia, PLoS ONE, 2015, 10, e0146026.
Taku Nakayama, Hodaka
Okajima, Tatsuya Kobayashi, Shimpei Otsuka, Motowo Nakajima, Tohru Tanaka and
Shun-ichiro Ogura
Intracellular heme increases in a manner dependent on cell density, ALA-Porphyrin Science, 2015, 4, 13-17.
Yutaka Yonemura, Yoshio
Endo, Emel Canbay, Yang Liu, Haruaki Ishibashi, Kazuyoshi Takeshita, Akiyoshi
Mizumoto, Masamitu Hirano, Nobuyuki Takao, Masumi Ichinose, Yan Li and
Shun-ichiro Ogura
Selection of patients by membrane transporter expressions for aminolevulinic acid
(ALA)-guided photodynamic detection of peritoneal metastases, International Journal of Sciences, 2015,
4, 66-77.
Shihu Wei, Hideo Fukuhara,
Chiaki Kawada, Atsushi Kurabayashi, Mutsuo Furihata, Shun-ichiro Ogura, Keiji
Inoue and Taro Shuin
Silencing of ATPase inhibitory factor 1 inhibits cell growth via cell cycle arrest
in bladder cancer, Pathobiology,
2015, 82, 224-232.
Takashi Sawamura, Tatsumi
Tanaka, Hiroyuki Ishige, Masayuki Iizuka, Yasutoshi Murayama, Eigo Otsuji,
Akihiro Ohkubo, Shun-ichiro Ogura and Hideya Yuasa
The effect of coatings on the affinity of lanthanide nanoparticles to MKN45 and
HeLa cancer cells and improvement in photodynamic therapy efficiency, International Journal of Molecular Sciences,
2015, 16, 22415-22424.
Mai Miura, Kensuke Ito,
Maiko Hayashi, Motowo Nakajima, Tohru Tanaka and Shun-ichiro Ogura*
The effect of 5-aminolevulinic acid on cytochrome P450-mediated prodrug activation,
PLoS ONE, 2015, 10, e0131793.
Maiko Hayashi, Hideo
Fukuhara, Keiji Inoue, Taro Shuin, Yuichiro Hagiya, Motowo Nakajima, Tohru
Tanaka and Shun-ichiro Ogura*
The effect of iron ion on the specificity of photodynamic therapy with 5-aminolevulinic
acid, PLoS ONE, 2015, 10, e0122351.
Kentaro Matsumoto, Yuichiro
Hagiya, Yoshio Endo, Motowo Nakajima, Masahiro Ishizuka, Tohru Tanaka and
Shun-ichiro Ogura*
Effects of plasma membrane ABCB6 on 5-aminolevulinic acid (ALA)-induced
porphyrin accumulation in vitro: Tumor cell response to hypoxia, Photodiagnosis and Photodynamic Therapy,
2015, 12, 45-51.
Urara Ota, Hideo Fukuhara,
Masahiro Ishizuka, Fuminori Abe, Chiaki Kawada, Kenji Tamura, Tohru Tanaka,
Keiji Inoue, Shun-ichiro Ogura* and Taro Shuin
Plasma protoporphyrin IX following administration of 5-aminolevulinic acid as a
potential tumor marker, Molecular and
Clinical Oncology, 2015, 3, 797-801.
Junkoh Yamamoto, Shun-ichiro
Ogura, Shohei Shimajiri, Yoshiteru Nakano, Daisuke Akiba, Takehiro Kitagawa,
Kunihiro Ueta, Tohru Tanaka and Shigeru Nishizawa
5-Aminolevulinic acid-induced protoporphyrin IX with multi-dose ionizing
irradiation enhances host antitumor response and strongly inhibits tumor growth
in experimental glioma in vivo, Molecular
Medicine Reports, 2015, in press
2014年
Tomohiro Ikehata, Yuji
Onodera, Takashi Nunokawa, Tomohisa Hirano, Shun-ichiro Ogura, Toshiaki
Kamachi, Osamu Odawara and Hiroyuki Wada
Photodynamic therapy using upconversion nanoparticles prepared by laser
ablation in liquid, Applied Surface
Science, 2014, in press.
Taku
Chibazakura, Yui Toriyabe, Hiroshi Fujii, Kiwamu Takahashi, Mariko Kawakami,
Haruna Kuwamura, Hazuki Haga, Shun-ichiro Ogura, Fuminori Abe, Motowo Nakajima,
Hirofumi Yoshikawa and Tohru Tanaka
5-aminolevulinic acid enhances cell
death under thermal stress in certain cancer cell lines, Bioscience Biotechnology and Biochemistry, 2015, 79, 422-431.
Yang Liu, Yoshio Endo,
Takuji Fujita, Haruaki Ishibashi, Toshihiro Nishioka, Emel Canbay, Yan Li,
Shun-ichiro Ogura and Yutaka Yonemura
Cytoreductive surgery under aminolevulinic acid-mediated photodynamic
diagnosis plus hyperthermic intraperitoneal chemotherapy in patients with peritoneal
carcinomatosis from ovarian cancer and primary peritoneal carcinoma: Results of
a Phase I trial, Annals of Surgical
Oncology, 2014, 21, 4256-4262.
Kohei Yamashita, Yuichiro
Hagiya, Motowo Nakajima, Masahiro Ishizuka, Tohru Tanaka and Shun-ichiro Ogura*
The effects of the heme precursor 5-aminolevulinic acid (ALA) on REV-ERBα
activation, FEBS Open Bio, 2014, 4,
347-352.
Emel Canbay, Haruaki
Ishibashi, Shouzou Sako, Toshiyuki Kitai, Eisei Nishino, Masamitsu Hirano, Akiyoshi
Mizumoto, Yoshio Endo, Shun-ichiro Ogura and Yutaka Yonemura
Photodynamic detection and management of intraperitoneal spreading of primary
peritoneal papillary serous carcinoma in a man: report of a case, Surgery Today, 2014, 44, 373-377.
Yuta Sugiyama, Yuichiro
Hagiya, Motowo Nakajima, Masahiro Ishizuka, Tohru Tanaka and Shun-ichiro Ogura*
The heme precursor 5-aminolevulinic acid disrupts the Warburg effect in tumor
cells and induces caspase-dependent apoptosis, Oncology Reports, 2014, 31, 1282-1286.
2013年
Kensuke Ito, Yuichiro Hagiya, Masahiro Ishizuka, Motowo Nakajima, Tohru
Tanaka, and Shun-ichiro Ogura*
Protoporphyrin IX metabolized from 5-aminolevulinic acid decreased EGFR
expression levels via HSP90 inhibition, ALA-Porphyrin Science, 2013, 2, 43-46.
Hitoshi Nakagawa, Chiaki
Abe, Urara Ota, Tomoko Hiroi, Tomoki Ichikawa, Motowo Nakajima, Masahiro
Ishizuka, Tohru Tanaka and Shun-ichiro Ogura
The effect of molar ratio of 5-aminolevulinic acid and sodium ferrous citrate
on porphyrin-heme metabolism in normal cells, ALA-Porphyrin Science, 2013, 2, 37-41.
Keisuke Komatsuya, Masayuki
Hata, Emmanuel O Balogun, Kenji Hikosaka, Shigeo Suzuki, Kiwamu Takahashi,
Tohru Tanaka, Motowo Nakajima, Shun-ichiro Ogura, Shigeharu Sato and Kiyoshi
Kita
Synergy of ferrous ion on 5-aminolevulinic acid-mediated growth inhibition of
Plasmodium falciparum, Journal of Biochemistry,
2013, 154, 501-504.
Atsushi Shimoyama, Hiroya
Watase, Yu Liu, Shun-Ichiro Ogura, Yuichiro Hagiya, Kiwamu Takahashi, Katsushi
Inoue, Tohru Tanaka, Yasutoshi Murayama, Eigo Otsuji, Akihiro Ohkubo and Hideya
Yuasa
Access to a novel near-infrared photodynamic therapy through the combined use
of 5-aminolevulinic acid and lanthanide nanoparticles, Photodiagnosis and Photodynamic Therapy, 2013, 10, 607-614.
Keiji
Inoue, Urara Ota, Masahiro Ishizuka, Chiaki Kawada, Hideo Fukuhara, Taro Shuin,
Ichiro Okura, Tohru Tanaka and Shun-ichiro Ogura*
Porphyrins as urinary biomarkers for bladder cancer after 5-aminolevulinic acid
(ALA) administration: The potential of photodynamic screening for tumors, Photodiagnosis and Photodynamic
Therapy, 2013, 10, 484-489.
Yu Liu, Takuya Kobayashi,
Masayuki Iizuka, Tatsumi Tanaka, Izumi Sotokawa, Atsushi Shimoyama, Yasutoshi
Murayama, Eigo Otsuji, Shun-ichiro Ogura and Hideya Yuasa
Sugar-attached upconversion lanthanide nanoparticles: a novel tool for high-throughput
lectin assay, Bioorganic & Medicinal
Chemistry, 2013, 21, 2832-2842.
Yuichiro Hagiya, Hideo
Fukuhara, Kentaro Matsumoto, Yoshio Endo, Motowo Nakajima, Tohru Tanaka, Ichiro
Okura, Atsushi Kurabayashi, Mutsuo Furihata, Keiji Inoue, Taro Shuin and
Shun-ichiro Ogura*
Expression levels of PEPT1 and ABCG2 play key roles in 5-aminolevulinic acid (ALA)-induced
tumor-specific protoporphyrin IX (PpIX) accumulation in bladder cancer, Photodiagnosis and Photodynamic
Therapy, 2013, 10, 288-295.
Tomohisa Hirano, Yuichiro
Hagiya, Hideo Fukuhara, Keiji Inoue, Taro Shuin, Kentaro Matsumoto, Katsushi
Inoue, Tohru Tanaka, Ichiro Okura and Shun-ichiro Ogura*
Improvement of aminolevulinic acid (ALA)-mediated
photodynamic diagnosis using n-propyl
gallate, Photodiagnosis and Photodynamic
Therapy, 2013, 10, 28-32.
2012年
Yuta Sugiyama, Yuichiro Hagiya, Motowo Nakajima, Masahiro Ishizuka, Tohru Tanaka, Ichiro Okura and Shun-ichiro Ogura*
The effect of aerobic respiration activity on porphyrin metabolism in tumor cells,
ALA-Porphyrin Science, 2012, 2,
67-72.
Shigenobu Yano, Hiromi Ohi,
Mizue Ashizaki, Makoto Obata, Yuji Mikata, Rika Tanaka, Takanori Nishioka,
Isamu Kinoshita, Yuko Sugai, Ichiro Okura, Shun-ichiro Ogura, Justyna A.
Czaplewska, Michael Gottschaldt, Ulrich S. Schubert, Takuzo Funabiki, Keiko
Morimoto and Misaki Nakai
Syntheses, characterization, and antitumor activities of platinum(II) and palladium(II)
complexes with sugar-conjugated triazole ligands, Chemistry & Biodiversity, 2012, 9, 1903-1915.
Kanako
Wakabayashi-Nakao, Koji Maruyama, Hidee Ishii, Koji Muramatsu, Keiichi
Hatakeyama, Keiichi Ohshima, Shun-ichiro Ogura, Takashi Nakajima, Ken Yamaguchi
and Tohru Mochizuki
Investigation of proNT/NMN secretion from small cell lung carcinoma cells using
a mouse xenograft model, Oncology Reports,
2012, 28, 1181-1186.
Keiichi
Hatakeyama, Kanako Wakabayashi-Nakao, Yutaka Aoki, Shun-ichiro Ogura, Ken
Yamaguchi, Takashi Nakajima, Taka-Aki Sato, Tohru Mochizuki and Isamu Hayashi
Novel protein extraction approach using micro-sized chamber for evaluation of
proteins eluted from formalin-fixed paraffin-embedded tissue sections, Proteome Science, 2012, 10, 19.
Junkoh Yamamoto, Shun-ichiro
Ogura, Tohru Tanaka, Takehiro Kitagawa, Yoshiteru Nakano, Takeshi Saito, Mayu
Takahashi, Daisuke Akiba and Shigeru Nishizawa
Radiosensitizing
effect of 5-aminolevulinic acid-induced protoporphyrin IX in glioma cells in
vitro, Oncology Reports, 2012, 27,
1748-52.
Kentaro Matsumoto, Yuichiro Hagiya, Hiroshi Nakagawa, Toshihisa Ishikawa,
Ichiro Okura and Shun-ichiro Oguraa*
Screening of transporters involved in porphyrin accumulation
after administration of 5-aminolevulinic acid in vitro, ALA-Porphyrin
Science, 2012, 1, 11-15.
Yuta
Sugiyama, Yuichiro Hagiya, Tetsuya Hayashi, Kyoko Tsuchiya, Masahiro Ishizuka,
Tohru Tanaka, Ichiro Okura and Shun-ichiro Ogura*
The effect of 5-aminolevulinic acid on cytochrome c oxidase activity, ALA-Porphyrin
Science, 2012, 1, 17-21.
Yuichiro Hagiya, Yoshio Endo, Yutaka Yonemura, Ichiro Okura and Shun-ichiro
Oguraa*
Tumor suppressor protein p53-dependent cell death induced by 5-aminolevulinic
acid (ALA)-based photodynamic sensitization of cancer cells in vitro, ALA-Porphyrin Science, 2012, 1, 23-31.
Yuichiro
Hagiya, Yoshio Endo, Yutaka Yonemura, Kiwamu Takahashi, Masahiro Ishizuka,
Fuminori Abe, Tohru Tanaka, Ichiro Okura, Motowo Nakajima, Toshihisa Ishikawa
and Shun-ichiro Ogura*
Pivotal roles of peptide transporter PEPT1 and ATP-binding cassette (ABC) transporter
ABCG2 in 5-aminolevulinic acid (ALA)-based photocytotoxicity of gastric cancer cells
in vitro, Photodiagnosis and Photodynamic Therapy, 2012, 9, 204-214.
2011年
Kenkichi
Takahashi, Naokado Ikeda, Naosuke Nonoguchi, Yoshinaga Kajimoto, Shin-ichi
Miyatake, Yuichiro Hagiya, Shun-ichiro Ogura, Hiroshi Nakagawa,
Toshihisa Ishikawa and Toshihiko Kuroiwa
Enhanced expression of coproporphyrinogen oxidase in malignant brain tumors:
CPOX expression and 5-ALA-induced fluorescence, Neuro-oncology, 2011, 13 (11), 1234-43.
Masahiro
Ishizuka, Yasunobu Ueda, Satoshi Utsugi, Shun-ichiro Ogura, Masao Kondo and
Ichiro Okura
Potential for cancer diagnosis by porphyrin determination after
5-aminolevulinic acid (ALA) administration –Establishment of a porphyrin
determination method, Porphyrins,
2011, 19 (2-3), 11-19.
Masahiro
Ishizuka, Yuichiro Hagiya, Yasuhiro Mizokami, Kanako Honda, Kenji Tabata,
Toshiaki Kamachi, Kiwamu Takahashi, Fuminori Abe, Tohru Tanaka, Motowo
Nakajima, Shun-ichiro Ogura*
and Ichiro Okura
Porphyrins in mouse urine after administration of 5-aminolevulinic acid as a
potential tumor marker, Photodiagnosis
and Photodynamic Therapy, 2011, 8, 328-331.
Shun-ichiro Ogura*,
Kouji Maruyama, Yuichiro Hagiya, Yuta Sugiyama, Kyoko Tsuchiya, Kiwamu
Takahashi, Fuminori
Abe, Kenji Tabata, Ichiro Okura, Motowo Nakajima and Tohru Tanaka
The
effect of 5-aminolevulinic acid on cytochrome c oxidase activity in mouse liver, BMC Research Notes, 2011, 4, 66.
Keiichi Hatakeyama,
Keiichi Ohshima, Yorikane Fukuda, Shun-ichiro Ogura, Masanori Terashima,
Ken
Yamaguchi and Tohru Mochizuki
Identification of a novel protein isoform derived from cancer-related splicing variants
using combined analysis of transcriptome and proteome, Proteomics, 2011, 11, 2275-82.
Takao Kunii, Shun-ichiro Ogura, Masayasu Mie and Eiry
Kobatake
Selection
of DNA aptamers recognizing small cell lung cancer using living cell-SELEX, Analyst, 2011, 136, 1310–1312.
2010年
Keiichi Ohshima, Kanako Inoue, Akemi Fujiwara, Keiichi Hatakeyama, Kaori Kanto, Yuko Watanabe, Koji Muramatsu, Yorikane Fukuda, Shun-ichiro Ogura, Ken Yamaguchi and Tohru Mochizuki
Let-7
microRNA family is selectively secreted into the extracellular environment via
exosomes in a metastatic gastric cancer cell line, PLoS ONE, 2010, 5, e13247.
2009年
Shun-ichiro Ogura, Masahiro Ishizuka, Yasuhiro Mizokami, Kanako Honda,
Kenji Tabata, Toshiaki Kamachi, Tohru Mochizuki and Ichiro Okura
Analysis of porphyrins in mouse plasma after administration of 5-aminolevulinic
acid as a potential tumor marker, Porphyrins,
2009, 18 (2-3), 25-30.
Hideaki
Takata, Hitoshi Nishijima, Shun-ichiro Ogura, Takehisa Sakaguchi, Paula A.
Bubulya, Tohru Mochizuki and Kei-ichi Shibahara
Proteome analysis of human nuclear insoluble fractions, Genes to Cells, 2009, 14, 975–990.
2008年
Shun-ichiro Ogura, Kumi Kaneko, Shoji Miyajima, Keiichi Ohshima, Ken Yamaguchi
and Tohru Mochizuki
Proneurotensin/neuromedin N secreted from small cell lung carcinoma cell lines
as a potential tumor marker, Proteomics
Clinical Applications, 2008, 2, 1620-1627.
Yuichiro Hagiya, Tatsuhiko Adachi, Shun-ichiro
Ogura, Ran An, Ai Tamura, Hiroshi Nakagawa, Ichiro Okura, Tohru Mochizuki and
Toshihisa Ishikawa
Nrf2-dependent induction of human ABC transporter ABCG2 and heme oxygenase-1 in
HepG2 cells by photoactivation of porphyrins: Biochemical implications for
cancer cell response to photodynamic therapy, Journal of Experimental Therapeutics and Oncology, 2008, 7 (2),
153-167.
2007年
Kazuya
Ogawa, Joanne T. Dy, Yoshiaki Kobuke, Shun-ichiro Ogura and Ichiro Okura
Singlet oxygen generation and photocytotoxicity against tumor cell by
two-photon absorption, Molecular Crystals and Liquid Crystals, 2007, 471
(1), 61-67.
Kohei
Maruyama, Haruko Takeyama, Tetsushi Mori, Keiichi Ohshima, Shun-ichiro Ogura,
Toru Mochizuki and Tadashi Matsunaga
Detection
of epidermal growth factor receptor (EGFR) mutations in
non-small cell lung cancer (NSCLC) using a fully automated system with a
nano-scale engineered biomagnetite, Biosensors and
Bioelectronics, 2007, 22 (9-10), 2282-2288.
2006年
Kazuya
Ogawa, Hideki Hasegawa, Yusuke Inaba, Yoshiaki Kobuke, Hideyuki Inouye,
Yoshihiko Kanemitsu, Eiji Kohno, Toru Hirano, Shun-ichiro Ogura and Ichiro
Okura
Water-soluble bis(Imidazolylporphyrin) self-assemblies with large two-photon
absorption cross sections as potential agents for photodynamic therapy, J. Med. Chem., 2006, 49, 2276-2283.
2005年
Kaori Takahashi, Shun-ichiro Ogura, Kenji Tabata, Toshiaki Kamachi and
Ichiro Okura
Localization and photodynamic activity of poly-L-lysine-chlorin conjugate for
tumor-bearing mouse, Porphyrins,
2005,14, 139-142.
Shun-ichiro
Ogura, Toshiaki Kamachi and Ichiro Okura
Cellular
localization and photodynamic effect of chlorin e6-monoclonal antibody
conjugate, J. Porphyrins and
Phthalocyanines, 2005, 9, 138-141.
Shiho
Hirohara, Makoto Obata, Shun-ichiro Ogura, Ichiro Okura, Suguru Higashida,
Chikara Ohtsuki, Shin-ichi Ogata, Yoshiko Nishikawa, Makiko Takenaka, Hiroshi
Ono, Yuji Mikata and Shigenobu Yano
Hydrophobicity parameters (Log P) of glycoconjugated porphyrins for
photodynamic therapy evaluated by reversed phase HPLC, J. Porphyrins and Phthalocyanines, 2005, 8, 1289-1292.
Shun-ichiro
Ogura, Keiko Yazaki, Kazuki Yamaguchi, Toshiaki Kamachi and Ichiro Okura
Localization of poly-L-lysine - photosensitizer conjugate in nucleus, J. Controlled Release, 2005, 103, 1-6.
Shiho Hirohara, Makoto
Obata, Shin-ichi Ogata, Chikara Ohtsuki, Suguru Higashida, Shun-ichiro Ogura,
Ichiro Okura, Makiko Takenaka, Hiroshi Ono, Yuko Sugai, Yuji Mikata, Masao
Tanihara and Shigenobu Yano
Cellular uptake and photocytotoxicity of glycoconjugated chlorines in HeLa
cells, J. Photochem. Photobiol. B:
Biology, 2005, 78, 7-15.
2004年
Shiho Hirohara, Makoto Obata, Atsuhiro Saito, Shin-ichi Ogata, Chikara
Ohtsuki, Suguru Higashida, Shun-ichiro Ogura, Ichiro Okura, Yuko Sugai,
Yuji Mikata, Masao Tanihara and Shigenobu Yano
Cellular uptake and photocytotoxicity of glycoconjugated porphyrins in HeLa
cells, Photochemistry Photobiology,
2004, 80, 301-308.
Takashi
Saito, Shun-ichiro Ogura, Toshiaki Kamachi and Ichiro Okura
Intracellular formation of zinc protoporphyrin in mitochondria and its
photodynamic effect, Porphyrins, 2004, 13(2), 71-76.
2002年
Tomokazu Koide,
Shun-ichiro Ogura and Ichiro Okrua
Cellular accumulation of zinc protoporphyrin and its photodynamic effect, Porphyrins, 2002, 11 (2), 31-34.
2001年
Shun-ichiro Ogura, Yutaka Fujita, Toshiaki Kamachi and Ichiro Okura
Preparation of chlorin e6-monoclonal antibody conjugate and its effect for
photodynamic therapy, J. Porphyrins
Phthalocyanines, 2001, 5(5), 486-489.
2000年
Shun-ichiro Ogura, Toshiaki Kamachi and Ichiro Okura
Preparation of zinc phthalocyanine-monoclonal antibody conjugates and its selective
accumulation for tumor, Porphyrins, 2000, 9 (3),
252-256.
Kazuo Oda, Shun-ichiro
Ogura and Ichiro Okura
Preparation of a water-soluble fluorinated zinc phthalocyanine and its effect
for photodynamic therapy, J. Photochem.
Photobiol. B: Biology, 2000, 59, 20-25.
1998年
Shun-ichiro Ogura, Toshiaki Kamachi and Ichiro Okura
Preparation of new phthalocyanine-immunoconjugate and its effect for photodynamic
therapy, Porphyrins, 1998, 7 (2),
389-394.
Yuji
Mikata, Yoko Onchi, Minako Shibata, Toyoji Kakuchi, Hiroshi Ono, Shun-ichiro
Ogura, Ichiro Okura and Shigenobu Yano
Synthesis and Phototoxic Property of Tetra- and Octa-Glycoconjungated
Tetra-phenylchlorins, Bioorganic and
Medicinal Chemistry Letters, 1998, 8, 3543 3548.
Sang-Kyung
Lee, Shun-ichiro Ogura, Yutaka Amao and Ichiro Okura
Oxygen Monitoring in Living Cells by Palladium Tetracarboxyphenylporphyrin
(PdTCPP), Porphyrins, 1998, 7 (1),
39-44.
Yuji
Mikata, Yoko Onchi, Kenji Tabata, Shun-ichiro Ogura, Ichiro Okura, Hiroshi Ono
and Shigenobu Yano
Sugar-Dependent Photocytotoxic Property of Tetra- and Octa-glycoconjugated
Tetraphenylporphyrins, Tetrahedron
Letters, 1998, 39, 4505-4508.
Yuji
Mikata, Mika Yokoyama, Shun-ichiro Ogura, Ichiro Okura, Masafumi Kawasaki,
Mizuo Maeda and Shigenobu Yano
Effect of side chain location in (2-aminoethyl)aminomethyl-2-phenylquinolines
as antitumor agents, Bioorganic and
Medicinal Chemistry Letters, 1998, 8, 1243-1248.
1997年
Kenji Tabata, Shun-ichiro Ogura and Ichiro Okura
Photodynamic efficiency of protoporphyrin IX: Comparison of endogenous
protoporphyrin IX induced by 5-aminolebulinic acid and exogenous protoporpyrin
IX, Photochemistry and Photobiology,
1997, 66 (6), 842-846.
Shun-ichiro
Ogura, Kenji Tabata, Toshiaki Kamachi and Ichiro Okura
The photodynamic efficiency of protoporphyrin IX for HeLa cells, Porphyrins, 1997, 6, 29-34.
I.II 総説・著書
1.
小倉俊一郎、井上啓史
5-アミノレブリン酸を用いたがんの光線力学診療
医学のあゆみ、医歯薬出版株式会社、2016、258、1054-1057.
2.
小倉俊一郎
5-アミノレブリン酸・ポルフィリンの生命科学
現代化学増刊5-アミノレブリン酸の化学と医学応用、東京化学同人、2015、pp3-8.
3.
小倉俊一郎
光増感剤を用いたがんの光線力学治療とがんの診断、色材協会誌、2015、88、416–418.
4.
湯浅英哉、小倉俊一郎
ランタニドナノ粒子を用いた光線力学治療技術の開発
化学工業、化学工業社、2015、66、571-574.
5.
小倉俊一郎
アミノレブリン酸が拓く化学と医療
現代化学、東京化学同人、2014、6、pp.36-39.
6.
Urara Ota, Hidemitsu Sugihara, Fuminori Abe, Motowo Nakajima,
Shun-ichiro Ogura and Tohru Tanaka
5-Aminolevulinic Acid (5-ALA): a precursor of heme -Fermentation, metabolism
and usage-, ALA-Porphyrin Science,
2013, 2, 3-17.
7.
Shun-ichiro
Ogura*, Yuichiro Hagiya, Kenji Tabata, Toshiaki Kamachi and Ichiro Okura
Improvement of tumor localization of photosensitizers for photodynamic therapy
and its application for tumor diagnosis, Current Topics in Medicinal Chemistry,
2012, 12, 176-184.
8.
Shun-ichiro Ogura*
Photodynamic screening of tumors using aminolevulinic acid, Aminolevulinic acid (Edited by Ichiro
Okura and Tohru Tanaka), SBI ALApromo, 2011, 169-176.
9. Shun-ichiro
Ogura*
Aminolevulinic acid and porphyrin biosynthesis, Aminolevulinic acid (Edited by Ichiro Okura and Tohru Tanaka), SBI
ALApromo, 2011, 3-9.
10.
Toshihisa Ishikawa, Kenkichi Takahashi, Naokado
Ikeda, Yoshinaga Kajimoto, Yuichiro Hagiya, Shun-ichiro Ogura, Shin-ichi Miyatake and Toshihiko Kuroiwa
Transporter-Mediated
drug interaction strategy for 5-aminolevulinic acid (ALA)-based photodynamic diagnosis
of malignant brain tumor: molecular design of ABCG2 inhibitors, Pharmaceutics, 2011, 3 (3), 615-635.
11.
Shigenobu
Yano, Shiho Hirohara, Makoto Obata, Yuichiro Hagiya, Shun-ichiro Ogura, Atsushi
Ikeda, Hiromi Kataoka, Mamoru Tanaka and Takashi Joh
Current states and future views in photodynamic therapy, Journal of Photochemistry and Photobiology C: Photochemistry Reviews,
2011, 12 (1), 46-67.
12. 田中徹、石塚昌宏、小倉俊一郎、井上克司
5-アミノレブリン酸を用いたPDD、PDTの現状と将来, Japanese Journal of Endourology, 2011,
24, 39-44.
13.
Masahiro Ishizuka, Fuminori Abe, Yuki Sano, Kiwamu
Takahashi, Katsushi Inoue, Motowo Nakajima, Takeo Kohda, Naoki Komatsu,
Shun-ichiro Ogura
and Tohru Tanaka
New development of 5-aminolevurinic acid (ALA) in
cancer diagnoses and therapy, International
Immunopharmacology, 2011,
11,
358-365.
14.
小倉俊一郎、大倉一郎
光増感剤を用いたがんの蛍光診断と光線力学治療
科学と工業, 2007, 81(1), 31-37.
15.
Shun-ichiro Ogura, Kenji Tabata, Kaoru Fukushima,
Toshiaki Kamachi and Ichiro Okura
Development of phthalocyanines for photodynamic
therapy, J. Porphyrins and Phthalocyanines, 2006,
10(9-10), 1116-1124.
16.
小倉俊一郎、大倉一郎
光線力学治療用光増感剤の開発
ケミカルエンジニアリング, 2006, 51(3), 415-419.
17.
小倉俊一郎、大倉一郎
光線力学治療用光増感剤の開発
ナノバイオエンジニアリング（杉本直己編）, 化学同人, 2004, pp.134-142.
18. 小倉俊一郎、大倉一郎
抗腫瘍抗体結合型光増感剤の開発
化学工業, 2003,
54(12), 916-921.
19. 小倉俊一郎、大倉一郎
新しい光増感剤の開発と癌の光線力学治療への応用
未来材料, 2002,
2(6), 30-35.
20. 小倉俊一郎、大倉一郎
がんのレーザー治療 光増感剤の開発
バイオサイエンスとインダストリー, 2000,
58(3), 26-28.
II. 招待講演
1.
小倉俊一郎
ポルフィリンを使ったがん診断と治療
: 第112回触媒討論会、秋田市、秋田大学、2013/9/18-20.
2.
Shun-ichiro Ogura
Development of photodynamic screening (PDS) for bladder cancers
: The 20th International SPACC Synposium, Cangchun, China, 2013/9/12-13.
3.
Shun-ichiro Ogura
Mitochondrial activation by 5-aminolevulinic acid (ALA)
: 7th World Congress on Prevention of Diabetes and its Complications, Madrid,
Spain, 2012/11/11-14.
4.
Shun-ichiro Ogura
Photodynamic screening (PDS) for tumors and the effect of aerobic metabolism of
aminolevulinic acid (ALA)
: Seventh International Conference on Porphyrins and Phthalocyanines (Chair:
Dongho Kim, Seoul, Korea), Jeju, Korea, 2012/7/1-6.
5.
Shun-ichiro Ogura
Analysis of porphyrins in mouse plasma/urine after administration of
5-aminolevulinic acid as a potential tumor marker
: The 17th International SPACC Synposium (Chair: Hideyuki J Majima, Kagoshima
Univ.), Kagoshima Univ., 2010/10/13-16.
6.
Shun-ichiro Ogura
Analysis of porphyrins in mouse plasma/urine after administration of
5-aminolevulinic acid as a potential tumor marker
: 2010 International Symposium on Advanced Biological Engineering (Chair: Prof.
Xin-Hui Xing, Tsinghua Univ., China), Tsinghua Univ., Beijing, 2010/7/23-24.
7.
小倉俊一郎
5－アミノレブリン酸（5-ALA）を用いた蛍光診断
: 第1回金沢脳腫瘍セミナー（代表者：浜田潤一郎（金沢大学医学部））、金沢市、ホテル日航金沢、2008/1/26.
8.
小倉俊一郎
プロテオミクス解析および代謝産物の解析による新規腫瘍マーカーの探索
: 第6回北陸ポストゲノム研究フォーラム（代表者：佐藤博（金沢大学がん研究所））、金沢市、金沢大学、2007/6/28.
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